Inferno

								
Harvard professor Robert Langdon wakes up in a hospital in Florence, Italy with a head wound and no memory of the last few days. Dr. Sienna Brooks, one of the doctors tending to him, reveals that he is suffering from amnesia. When Vayentha, a female assassin, shows up in the hospital and kills Dr. Marconi, Brooks helps Langdon escape, and they flee to her apartment.

After Brooks recounts the details of his admission to the hospital, Langdon finds a cylinder with a biohazard sign in his jacket and decides to call the U.S. consulate. He is told that they are searching for him and want his location. Per Brooks' guidance, he gives them a location across the street from her apartment to avoid getting Brooks more involved in his mysterious situation than she already is. Soon, Langdon sees Vayentha pull up to the location he gave the consulate. At this point, they both believe the U.S. government wants to kill him. Langdon then decides to open the container and finds a small medieval bone cylinder fitted with a hi-tech projector that displays a modified version of Botticelli's Map of Hell, which is based on Dante's Inferno. A trail of clues leads them toward the Old City.

The Palazzo Vecchio in Florence However, they are dismayed to find that a secretive team of soldiers, and the Florentine Carabinieri are also searching for them. They flee into a construction site near the Boboli Gardens where he examines the "Map of Hell" again, noticing several subtle changes to the layers. Langdon discovers a phrase from the painting The Battle of Marciano by Vasari, located in the Palazzo Vecchio. They manage to evade the soldiers and get into the Old City using the Vasari Corridor.

At the Palazzo, a custodian sees Langdon snooping around and gets the director of the museum, Marta Alvarez. Alvarez recognizes him, having met him and Ignazio Busoni, the director of Il Duomo, the previous night. She leads them up a set of stairs by The Battle of Marciano, and Langdon realizes the top of the stairs is on the same level as the words "cerca trova" in the Battle of Marciano painting. Alvarez tells him that she showed them Dante's death mask the previous night, which sits in a room down the hall from the Battle of Marciano painting. He realizes he is retracing his own steps from the previous night. Finding the mask gone, security footage shows Langdon and Busoni stealing the mask. Fleeing the guards, they listen to a message Busoni left telling him where the mask is hidden, referring to "Paradise 25"

Gates of Paradise at Florence Baptistry Langdon and Brooks escape the guards, but the soldiers arrive. They cross the attic over the Apotheosis of Cosimo I, where Brooks pushes Vayentha to her death. Langdon connects the phrase "Paradise 25" to the Florence Baptistry, where they find the Dante mask along with a riddle from its current owner, a billionaire geneticist named Bertrand Zobrist. She explains that Zobrist was a geneticist who advocated the halting of humanity's growth, due to its out of control population and that he was rumored to be working on a means to do so using an engineered disease. A man named Jonathan Ferris, with a large bruise on his chest which he hides from the two, and a severe rash on his face, claiming to be from the World Health Organization (WHO), comes and helps them escape the soldiers. They follow the riddle to Venice, where Ferris suddenly falls unconscious, with Brooks claiming he is suffering from massive internal bleeding, causing Langdon to suspect Ferris has been infected with Zobrist's plague. He is captured by a group of black-clad soldiers while she escapes.

Langdon is taken to Dr. Elizabeth Sinskey, the director-general of the WHO, and is given an explanation of what is going on: Zobrist, who committed suicide the week before, was a brilliant geneticist and Dante fanatic who had supposedly developed a new biological plague that will kill off a large portion of the world's population in order to quickly solve the problem of the world's impending overpopulation, citing the Doomsday Argument. Sinskey raided Zobrist's safe deposit box, found the cylinder and flew him to Florence to follow the clues. However, he stopped communicating with Sinskey after meeting with Alvarez and Ignazio and the WHO feared he betrayed them and was working with Zobrist to unleash the plague. The soldiers were the WHO's emergency response team and never meant to kill him.

Zobrist had paid a shadowy consulting group called The Consortium to protect the cylinder until a certain date. He also left a disturbing video filled with Dante imagery, which also showed a picture of the plague itself, kept in a hidden underwater location, within a slowly dissolving bag. The video claims that the world will be changed the following morning. When Sinskey took it away, they abducted Langdon and staged every event up to this point so that he would be motivated to solve it. The leader of The Consortium, having become aware of the bioterrorism plot, agrees to cooperate with the WHO. Ferris's rash was due to an allergic reaction to the spirit gum he used as part of the disguise as the doctor Vayentha "murdered." His bruises were because the squib used to simulate him being shot in the chest misfired and broke his ribs. He collapsed in Venice because he had been ordered to detain Brooks, as the Provost (Consortium head) had allied with Sinskey, with Brooks realizing and punching him in his damaged ribs.

Tomb of Enrico Dandolo, at the Hagia Sophia Brooks goes rogue and The Consortium realizes she was a secret supporter and lover of Zobrist. She learned where the plague was being kept after Langdon solved the riddle and acquires a private jet to get to it before everyone else. Langdon, the WHO and The Consortium team up to stop her. After watching Zobrist's video, they conclude that the bag containing the plague will be fully dissolved by the date the video specifies and that Zobrist's clues point to its location: the Hagia Sophia in Istanbul, where Enrico Dandolo is buried. He and the others find the plague is in the Cistern but discover that she is already there. The bag that held the plague had already been broken, presumably spreading through the outer world via visiting tourists. Brooks runs out of the Cistern yelling something in Turkish, which causes panic among the tourists who stampede out into the city while Langdon gives chase.

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